Frontline for Dogs Same as Frontline for Cats?

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This topic contains 40 replies, has 29 voices, and was last updated by  Moonshadow_NZ 1 year, 2 months ago.

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    Welcome to TDK, Steven. Your research looks very thorough. I’m sure many TDKers will find it helpful. 🙂


    Renee in Arkansas

    CINDY also got the larger dog kind with syring from vet



    We have used the frontline XL for dogs on our two cats for years, ever since they were kittens, you need to get a kit, I got mine on ebay for a few bucks. You can also buy your frontline on ebay, which I always do to save. Just make sure you know correct dose to put on cat.



    So what’s the verdict, 1/2cc of regular “Frontline” or of Frontline “PLUS” for dogs okay to put on a 10 to 14lb cat? I’m with you on the cost containment thing. I’m fostering 4 cats and 4 vials per month 12 months a year is simply too much to pay while i’m unemployed. Someone donated her Dog Frontline PLUS to me. I know from the Cat rescue groups, they routinely use the largest vial of plain Advantage for Dogs they can get and syringe exactly 0.9ml out to use on each on cat. I see the formulation, ingredients and amounts are different for Advantage vs Frontline. But for me it’s Frontline Plus or fleas, tapeworms and scabs all over. I’ve got to do it. So was the vet advice 0.5ml (same as 0.5cc=0.5ml=1/2ml) of Frontline or Frontline plus?



    ok, i keep all my old used packaging. and i’m comparing cat frontline plus (includes flea, ticks and lice control) to dog (45-88pounds) frontline plus. Same active ingredients in slightly different amounts. FPlus for cats is fipronil 9.8% and (S)-methoprene 11.8%, inert ingredients 78.4% whereas Dog FPlus is fipronil 9.8% and (S)-methoprene 8.8% which is slightly LESS, and 81.4% inert ingredients. So I am guessing, GUESSING, that if given the right dosage, it might be safe. But has anyone out there tried the F.PLUS on a 10lb cat safely. Some of the prior comments were unclear whether they were refering to frontline or frontline plus or the new frontline multi.

    The multi’s are probably closer to Revolution which also kills a certain worm and ear mites or mange i think). Just so everyone knows, there’s Advantage brands (various ones like Advantage multi), Frontline brands (including Fplus and Fmulti), the newer Revolution, the ingestible pill one, and one i see commercials now is Pet ARmour sold at Targets. Any feedback on that one as far as cost and if it works? Just FYI, Advanage regular uses Imidacloprid and Advantage Multi uses Imidacloprid + moxidectin, both different from Frontline”s. Some control heartworm, fleas, hookworms, roundworms, ear mites. I don’t see what the flea/heartworm/mange/ear mite/nematode worm killing ingredient in Revolution is. I think it’s selamectin but that could just be the generic name. For more info on revolution 1888 revolution, made by Pfizer.

    If anyone has connections to a vet willing to give true cost saving advice and repurcussions of off-use use of these meds to them, please post info… no need to name names for liability reasons as there is always a risk in altering use and dosage of medications and that’s why the companies don’t sell them in “family size” multi application jars…too risky, too many stupud people will overdose or underdose their pets and then sue them.



    I just used a syringe to measure .5 of Frontline to add to my 2 cats a few days ago and they are fine. HOWEVER last year my 4yo cat died a day after using the CAT FORMULA, but I don’t recall which brand nor do I know for sure if her death was from the flea control liquid. She had it in the past with no problems.

    I tried flea combing daily but couldn’t keep up.



    three months now using .25 ml Frontline Plus for 100 pounds dogs on my two 5-7 pounds kittens. 0 fleas, 2 happy cats and 1 richer owner



    This is what we use as well. i only use it, when i see a flea. so, this year, I don’t know that I’ve even used it. But, I should probably go ahead and start it since it’s getting warmer out here.

    My cats were about 4 weeks old when we started, with a much smaller dose though.



    I used small dosages of Advantage for dogs on my two cats for years and never had a flea or health problem. This was also vet reccomeneded and my kit was given by the vet. Ebay is a good source for the kit and also cheap flea medicine. The kits sold on ebay also gives a diagram on how much to put on your cats. I usually put a .5 on the syringe and apply it to the back of my cats neck. I also just bought a new pack of Frontline for dogs for $3.00 on ebay auction.




    Would you take your spouses/friends meds, No! Why would you risk the same for your pets?! (Esp a Toxic substance!!)

    Taken from Yahoo article:

    Significant Difference in Flea Meds for Dogs & Cats

    Not all flea medications utilize the same ingredients. Some chemicals that are approved for use in dogs may be toxic to cats and vice versa.

    Some medications utilize the same ingredients for dogs and cat medications, but the amount of chemicals in the formulas are different.

    Read more: Difference Between Dog & Cat Flea Meds |



    I am giving my cats and dogs frontline plus for dogs for many years, I checked the ingredients before and I measure it very careful . I think the makers of frontline and the vets want people not to use the same, to make sure that nobody makes a mistake and don’t give to much because that could be fatal. That’s why they also sell different sizes for different weights for dogs. Even I live in california , I usually stop the treatment in the winter for three to five month to give the pets a break and start when it gets hot again. So far it works well.



    A question about whether the dosage rule of .5 cc applies to Frontline or Frontline Plus: I know for sure that it applies to Frontline Plus. As Stephen J Klein’s reply correctly states, there is a little bit less of the second active ingredient in the dog version, and this is the ingredient used to kill ticks. In my experience, cats don’t get ticks stuck to themselves anywhere nearly as often as dogs, so this is an acceptable solution. For years, I have used the largest size dog dose, 4cc for dogs up to 123 lbs. I divide it into 8 doses by putting it into a sterile glass jar and using a syringe to draw .5 cc. That way I can treat my own cats plus fosters for about $12-$15 a month TOTAL.



    ok, I haven’t read all the answeres, so if I have repeated an answer, then I’m sorry. I have been looking around, and according to what I have read, you CAN use the dog version on cats. the danger is of overdose. they say that to use the dog version, you need EXACT dose of .5cc, no more. they say to do this you need a syringe to measure it with. hope this helps.



    After looking at prices of Frontline, Revelolution and Advantage and reading all the precautions I decided to not use any of them. Bought some Adams Flea and Tick spray but one cat had a terrible reaction to it, foaming at the mouth and hyper as all get out. I found capsules from Little City Dogs, Premium CHICKEN FLAVORED Flea Killer Capsules for CATS and DOGS 2 to 25 lbs. They worked great just as described. The fleas were dropping off dead in an hour. It’s a monthly dose but safe enough for daily use, and the best is you are able to mix with their soft food.



    A few months ago Jeff and I attempted to use Adams brand on the cats and after Oreo had a horrible reaction to it we returned the unused portion and demanded our money back. I wouldn’t recommend Adams to anyone for flea treatment! =(



    An Adams product is what nearly killed my cat Lady, years ago. She was in the vet hospital for more than a week, battling to regain liver function. She finally did. But that was my last experiment with OTC flea control medications.

    Of late, I’ve used diatomaceous earth to treat kitties, carpet, and any upholstered furniture/other soft surfaces. However, I’ve also been using Confortis on any of my pets who travel outside, and it seems to be working very well. It is an oral medication (liver flavored pill) that is dosed according to species and body weight, so you must go through a vet for it – but it seems reasonably priced, and also acts as a wormer. You might inquire of your vet as to his or her opinion. Active ingredient is a newer one, called spinosad, a spinosyn (non-antibacterial tetracyclic macrolides); the ingredient is derived from spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa.



    Frontline Plus Dog is not the same as Frontline Cat….Frontline Plus Cat has more active ingredients than the dog version.

    They are identical except for higher IGR (Insect Grow Regulator) for the cats due to cats being a terrific carrier of fleas.

    If someone does not have the proper way to weigh and measure the EXACT amount to treat the animal then they will likely under treat or over treat the animal wasting product. Frontline is NOT absorbed into the body proper of the animal. It is absorbed into the oil glands at the ends of the hair and then slowly released. The LD50 (Lethal Dose 50% kills) for Fipronil is insanely high. When getting registered as a pesticide it was impossible to kill the test rats with an overdose orally or dermal even though rodents absorb chemicals through their skin at insanely high rates(that’s one reason they are used as test dummies)…they literally had to blow the rats up with a feeding tube to get it to kill the test rats. Mammals process Fipronil fast if ingested (24/48hrs). The average cat would have to consume 89 .017z tubes to reach LD50. Again LD50 being the death of 50% of the animals. This is NOT to say the animal will not be sick if a lower dosage is consumed.

    Frontline Plus Cat & Dog is ethanol based and if not properly sealed after application will evap. quite quickly leading to overdosage/waste of product. A small glass vial with screw on lid works well and a large bore syringe as a topical applicator.



    This is from the Frontine web site

    Can I use the FRONTLINE Plus for Cats on my dogs and the FRONTLINE Plus for Dogs on my cats?

    FRONTLINE Plus for Cats and FRONTLINE Plus for Dogs are not exactly the same. Only use the appropriate product for your dog or cat. However, FRONTLINE SPRAY can be used on both dogs and cats.

    I have treated my cat with FRONTLINE Plus for Large Dogs by mistake. Will it harm him?

    FRONTLINE Plus has a long established and wide margin of safety and your cat should be fine. There is no need to stress your cat by bathing him, but if you have recently applied the product you can dab off any excess on the back of the neck with a tissue. If you have any concerns about your pet please contact your local veterinarian or call us on 0800-800-822

    Ok so wide margin of safety and the animal will be fine so why not. It seems to be a marketing thing or one like the testing on toys for under three. The toy may be perfectly safe just not tested.



    I too, for quite sometime time, have been using the Frontline for dogs to save money, on my 11lb cat but as the concentration of the 2nd active ingredient in Frontline for cats, S-Methoprene at 11.8%, equates to 20% more concentration than that used in Frontline for dogs, I am making a personal decision to use the Frontline for cats only from now on.



    WoW! First of all I gta say, there are some seriously emotional responses posted here that lack any scientific support.
    Secondly, both medications contain the same active ingredients w the primary (fipronil) being identical in concentration. The second is actually more concentrated in the feline version…
    Third, the baseline dosage for frontline/petarmor is 0.0305mL per pound. So, if you want to be 100% accurate on dosage, for both species, simply multiply the weight of your pet by 0.0305.
    (8Lbs cat = 0.24mL dose)
    (120Lbs dog = 3.81mL dose)

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