Choosing kittens from a litter, which one?

Hello from The Netherlands.

I found your board by searching for an answer to my question. And I’m very much hoping you guys can help me out. I didn’t want to post this question on other forums I frequent because people are somewhat harsh towards the breed we chose.

We lost both our girls in the space of 9 weeks. Both were born 10 weeks apart, by different moms. They came from a local shelter and they lived to the age of 15. We miss them very, very much.
But we’ve decided our house is so empty and cold without cats. So we searched for a catbreed that suited us and our lifestyle.
We came across the Ragdoll and like them very much. We also found a breeder quite near to us (a couple of miles north) and started asking her a few questions. She told us she was expecting a litter in the second week of december. A few days after the litter was born she sent us photo’s showing 3 small balls of fur. One a bit smaller then the two others.
Now, three weeks later she sent us a video of the three with their mom. Of course we are both completely in love. She told us that one of the boys is smaller than the other two and that the two big boys are giants.
And this is showing on the video. Two are bigger than her hand and one is half the size. But the smallest is the most beautiful boy I’ve seen.

And this brings me to my question; Is it a problem if we chose the runt of the litter over the two big boys? Will we have to expect more health problems in runts? I couldn’t really find any answers to this, so I’m hoping you guys have any ideas about it.

Thanks in advance!